Hutchinson, P.J.Kolias, A.G.Tajsic, T.Adeleye, A.Aklilu, A.T.Apriawan, T.Bajamal, A.H.Barthélemy, E.J.Devi, B.I.Bhat, D.Bulters, D.Chesnut, R.Citerio, G.Cooper, D.J.Czosnyka, M.Edem, I.El-Ghandour, N.M.F.Figaji, A.Fountas, K.N.Gallagher, C.et al.2025-07-172025-07-172019Acta Neurochirurgica, 2019; 161(7):1261-12740001-62680942-0940https://hdl.handle.net/2440/146099Background: Two randomised trials assessing the effectiveness of decompressive craniectomy (DC) following traumatic brain injury (TBI) were published in recent years: DECRA in 2011 and RESCUEicp in 2016. As the results have generated debate amongst clinicians and researchers working in the field of TBI worldwide, it was felt necessary to provide general guidance on the use of DC following TBI and identify areas of ongoing uncertainty via a consensus-based approach. Methods: The International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury took place in Cambridge,UK, on the 28th and 29th September 2017. The meetingwas jointly organised by theWorld Federation of Neurosurgical Societies (WFNS), AO/Global Neuro and the NIHR Global Health Research Group on Neurotrauma. Discussions and voting were organised around six pre-specified themes: (1) primary DC for mass lesions, (2) secondary DC for intracranial hypertension, (3) peri-operative care, (4) surgical technique, (5) cranial reconstruction and (6) DCin low- andmiddle-income countries. Results: The invited participants discussed existing published evidence and proposed consensus statements. Statements required an agreement threshold of more than 70% by blinded voting for approval. Conclusions: In this manuscript, we present the final consensus-based recommendations. We have also identified areas of uncertainty, where further research is required, including the role of primary DC, the role of hinge craniotomy and the optimal timing and material for skull reconstruction.en© The Author(s) 2019. Open Access This article is distributed under the terms of the Creative Commons At tribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.Neurosurgery; Neurotrauma; Decompression; CranioplastyHumansIntracranial HypertensionConsensusDecompressive CraniectomyBrain Injuries, TraumaticJournal article10.1007/s00701-019-03936-y2024-06-12475133Wells, A. [0000-0002-4373-347X]