Brotherton, P.Endicott, P.Beaumont, M.Barnett, R.Austin, J.Cooper, A.Sanchez, J.2009-10-292009-10-292008Forensic Science International: Genetics Supplement Series, 2008; 1(1):19-211875-17681875-175Xhttp://hdl.handle.net/2440/51618High levels of non-authentic sequence data can be generated by traditional PCR-based methodologies when DNA is damaged, template numbers are small and/or the target amplification size too large. We therefore present an alternate methodology based on single primer extension (SPEX) amplification; that places no pre-defined size constraints on amplification and interacts with only one of the DNA strands at the target locus. © 2008 Elsevier Ireland Ltd. All rights reserved.enDNA damageGenotypingLow copy number DNASNPsSingle primer extension (SPEX) amplification to accurately genotype highly damaged DNA templatesJournal article002008391810.1016/j.fsigss.2007.10.1112-s2.0-5064908979041074Austin, J. [0000-0003-4244-2942]Cooper, A. [0000-0002-7738-7851]