Milte, R.Miller, M.Crotty, M.Mackintosh, S.Thomas, S.Cameron, I.Whitehead, C.Kurrle, S.Ratcliffe, J.2018-10-052018-10-052016Journal of Rehabilitation Medicine, 2016; 48(4):378-3851650-19771651-2081http://hdl.handle.net/2440/114855Epub ahead of print Mar 17, 2016Objective: To undertake a cost-utility analysis of the Individual Nutrition Therapy and Exercise Regime: A Controlled Trial of Injured, Vulnerable Elderly (INTERACTIVE) trial. Design: Cost-utility analysis of a randomized controlled trial. Subjects: A total of 175 patients following a hip fracture were allocated to receive either alternate weekly visits from a physical therapist and dietitian (intervention group), or social visits for 6 months (control group). Methods: Costs for utilization of hospitals, health and community services were compared with quality-adjusted life years gained, calculated from responses to the Assessment of Quality of Life instrument. Results: There were minimal differences in mean costs between the intervention ($AUD 45,331 standard deviation (SD): $AUD 23,012) and the control group ($AUD 44,764 SD: $AUD 20,712, p = 0.868), but a slightly higher mean gain in quality-adjusted life years in the intervention group (0.155, SD: 0.132) compared with the control group (0.139, SD: 0.149, p = 0.470). The incremental cost-effectiveness ratio was $AUD 28,350 per quality-adjusted life year gained, which is below the implied cost-effectiveness threshold utilized by regulatory authorities in Australia. Conclusion: A comprehensive 6-month programme of therapy from dietitians and physical therapists could be provided at a relatively low additional cost in this group of frail older adults, and the incremental cost-effectiveness ratio indicates likely cost-effectiveness, although there was a very high level of uncertainty in the findings.en© 2016 The Authors. Journal Compilation © 2016 Foundation of Rehabilitation Information. Journal of Rehabilitation Medicine is an immediately Open Access journal. Creative Commons licence used: CC BY-NC All articles are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.Hip fracture; rehabilitation; cost-utility analysis; nutrition therapyJournal article003009862010.2340/16501977-20700003724561000092-s2.0-84962215408254894Ratcliffe, J. [0000-0001-7365-1988]