Dredge, B.Polydorides, A.Darnell, R.2007-07-052007-07-052001Nature Reviews Neuroscience, 2001; 2(1):43-501471-003X1471-0048http://hdl.handle.net/2440/34840Splicing of pre-messenger RNA is regulated differently in the brain compared with other tissues. Recognition of aberrations in splicing events that are associated with neurological disease has contributed to our understanding of disease pathogenesis in some cases. Neuron-specific proteins involved in RNA splicing and metabolism are also affected in several neurological disorders. These findings have begun to bridge what we know about the mechanisms regulating neuron-specific splicing and our understanding of neural function and disease.en© 2001 Nature Publishing GroupBrainNeuronsAnimalsHumansNervous System DiseasesRNA-Binding ProteinsRNA PrecursorsAlternative SplicingJournal articleRQF000021610.1038/3504906113823Dredge, B. [0000-0002-6103-5165]