Immunogenicity and safety of measles-mumps-rubella and varicella vaccines coadministered with a fourth dose of Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine in toddlers: a pooled analysis of randomized trials

Bryant, K.McVernon, J.Marchant, C.Nolan, T.Marshall, G.Richmond, P.Marshall, H.Nissen, M.Lambert, S.Aris, E.Mesaros, N.Miller, J.2012-10-142012-10-142012Human Vaccines and Immunotherapeutics, 2012; 8(8):1036-10412164-554X2164-554Xhttp://hdl.handle.net/2440/73562A pooled analysis was conducted of 1,257 toddlers who received a fourth dose of Haemophilus influenzae type b-Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine (HibMenCY-TT ) or Hib conjugate vaccine (Hib polysaccharide conjugated to N. meningitidis outer membrane protein) coadministered with measles-mumps-rubella (MMR) and varicella (VAR) vaccines (NCT00134719/NCT00289783). Noninferiority of immunological responses to MMR and VAR was demonstrated between groups and incidences of MMR- and VAR-specific solicited symptoms were similar, indicating that HibMenCY-TT can be coadministered with MMR and VAR.en© 2012 Landes BioscienceHaemophilus influenzae tybe bNeisseria meningitidis scrogroups C and YMMRvaricellavaccinationtoddlersImmunogenicity and safety of measles-mumps-rubella and varicella vaccines coadministered with a fourth dose of Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine in toddlers: a pooled analysis of randomized trialsJournal article002012155210.4161/hv.203570003080381000132-s2.0-8486611880723399Marshall, H. [0000-0003-2521-5166]