Arstall, Margaret Anne2006-12-282006-12-2819951995http://hdl.handle.net/2440/18677Includes addendum and corrections (leaves 390-402)Bibliography: leaves 333-389.xv, 402 leaves : ill. ; 30 cm.Analyses the effects of N-acetylcysteine (NAC) alone and in combination with glyceryl trinitrate (GTN) on three models of myocardial ischaemia and reperfusion. A sensitive and specific assay for malondialdehyde (MDA) in plasma was developed in order to assess the extent of oxidative stress in this series of studies.570673 bytesapplication/pdfen616.123 20Coronary heart disease Effects of drugs on.Myocardial reperfusion Effects of drugs on.Oxidation, Physiological Effects of drugs on.Thesis