Tanner, M.S.De Guingand, D.Reddy, M.Rowson, S.Rolnik, D.L.Da Silva Costa, F.Davey, M.A.Mol, B.W.Wallace, E.M.Palmer, K.R.2021-11-262021-11-262021Hypertension in Pregnancy, 2021; 40(4):336-3451064-19551525-6065https://hdl.handle.net/2440/133417Published online: 26 Oct 2021Objective:To compare the effect of comorbidities on the phenotype and outcomes of preeclampsia. Methods:A matched retrospective cohort study of women delivering at a tertiary maternity center following a diagnosis of preeclampsia. We collected data on signs and symptoms, biochemical markers, and maternal and perinatal outcomes. Results:We studied 474 women; 158 women with and 316 without comorbidities. Compared to women without comorbidities, women with comorbidities delivered earlier. They suffered fewer maternal but more neonatal complications. Conclusion:Women with comorbidities receive earlier intervention than women without comorbidities, which may lead to fewer maternal complications but worse neonatal outcomes.en© 2021 Informa UK Limited, trading as Taylor & Francis GroupPreeclampsia; hypertension; angiogenic; complications; comorbiditiesJournal article10.1080/10641955.2021.19913712021-11-26593291Mol, B.W. [0000-0001-6887-0262] [0000-0001-8337-550X]