Alexander, L.Cooper, K.Peters, M.D.Tricco, A.C.Khalil, H.Evans, C.Munn, Z.Pieper, D.Godfrey, C.M.McInerney, P.Pollock, D.2024-07-252024-07-252024Journal of Clinical Epidemiology, 2024; 170(111343):111343-1-111343-70895-43561878-5921https://hdl.handle.net/2440/141654Published online 4 April 2024Scoping reviews can identify a large number of evidence sources. This commentary describes and provides guidance on planning, conducting, and reporting large scoping reviews. This guidance is informed by experts in scoping review methodology, including JBI Scoping Review Methodology group members, who have also conducted and reported large scoping reviews. We propose a working definition for large scoping reviews that includes approximately 100 sources of evidence but must also consider the volume of data to be extracted, the complexity of the analyses and purpose. We pose six core questions for scoping review authors to consider when planning, developing, conducting, and reporting large scoping reviews. By considering and addressing these questions, scoping review authors might better streamline and manage the conduct and reporting of large scoping reviews from the planning to publishing stage.en© 2024 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).CommentaryEvidence synthesisguidancemethodologyMethodsScoping reviewHumansResearch DesignReview Literature as TopicJournal article10.1016/j.jclinepi.2024.1113432024-07-192-s2.0-85190998198689751Peters, M.D. [0000-0002-1108-3783]Munn, Z. [0000-0002-7091-5842]Pollock, D. [0000-0002-6604-0609]