Shearwin, K.Egan, J.2006-07-052006-07-051996Journal of Biological Chemistry, 1996; 271(19):11525-115310021-92581083-351Xhttp://hdl.handle.net/2440/11317The CI repressor protein, responsible for maintenance of the lysogenic state, and the Apl protein, required for efficient prophage induction, are the two control proteins of the lysis-lysogeny transcriptional switch of coliphage 186. These proteins have been overexpressed, purified, and their self-association behavior examined by sedimentation equilibrium. Phage 186 CI dimers self-associate in solution through tetramers to octamers in a concerted process. The Apl protein of 186 is an unusual example of a helix- turn-helix protein which is monomeric in solution.enJournal article0030004388001996542310.1074/jbc.271.19.11525A1996UJ944000732-s2.0-1584439094868394Shearwin, K. [0000-0002-7736-2742]