Hill, E.Clifton, P.Goodwill, A.M.Dennerstein, L.Campbell, S.Szoeke, C.2025-12-182025-12-182018Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2018; 4(1):535-5412352-87372352-8737https://hdl.handle.net/11541.2/134977Introduction: Evidence indicates that associations between diet and Alzheimer’s disease may occur through biomarker pathways such as amyloid-b (Ab); however, few studies have investigated dietary/Ab relationships, and no study has investigated this relationship in women. Methods: Dietary patterns were extrapolated for 115 participants from the Women’s Health Aging Project. Aβ deposition was measured via in vivo F-18 florbetaben positron emission tomography scanning. Results: Participants were, on average, aged 70 years (62.63 SD), had 13 years of education (63.57SD), a BMI of 28 kg/m2 (65.46 SD), and a daily energy intake of 5161 kJ (61679.03 SD). Four dietarypatterns were identified: high fat, Mediterranean, junk food, and low fat. Adherence to the junk food diet was a significant predictor of Aβ deposition (β = .10, P = .03). Discussion: This study highlights the potential of diet to influence neurodegenerative disease and as a potential modifiable lifestyle risk factor for Alzheimer’s disease.enCopyright 2018 The Authors This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)biomarkersAlzheimer’s diseaseneuropathologyβ -amyloid proteindietnutritiondietary patternfactor analysiswomenJournal article10.1016/j.trci.2018.09.0072-s2.0-85055501357Clifton, P. [0000-0002-6411-626X]