Structural reassignment of Cytosporolides A - C via biomimetic synthetic studies and reinterpretation of NMR data

Spence, J.George, J.2012-05-162012-05-162011Organic Letters, 2011; 13(19):5318-53211523-70601523-7052http://hdl.handle.net/2440/70984A structure revision for the recently isolated fungal meroterpenoids, cytosporolides A-C, is suggested based on biosynthetic speculation and reinterpretation of existing spectroscopic data. The structure revision is supported by a biomimetic synthetic study, featuring a [4 + 2] cycloaddition reaction between a presumed o-quinone methide intermediate and β-caryophyllene.en© 2011 American Chemical SocietySesquiterpenesMagnetic Resonance SpectroscopyMolecular StructureCyclizationBiomimetic MaterialsPolycyclic SesquiterpenesStructural reassignment of Cytosporolides A - C via biomimetic synthetic studies and reinterpretation of NMR dataJournal article002011255310.1021/ol202181g0002953139000872-s2.0-8005477395127837George, J. [0000-0002-7330-2160]