Settasatian, Nongnuch2006-12-282006-12-2820012001http://hdl.handle.net/2440/21687Errata attached to inside front cover.Bibliography: leaves 112-166.xi, 166 leaves : ill. (some col.) ; 30 cm.This thesis is concerned with the interaction of the plasma factor, phospholipid transfer protein (PLTP) with HDL. The studies described in this thesis define the mechanism of the remodelling of reconstitute HDL (rHDL) by PLTP and the reasons why triglyceride enrichment of rHDL enhances the remodelling process. Other studies describe why triglyceride enrichment of rHDL enhances PLTP-mediated phospholipid transfers. In conclusion, this thesis describes the mechanism of the PLTP-mediated remodelling of rHDL and presents reasons why the remodelling is enhanced in particles that are enriched with triglyceride.161076 bytesapplication/pdfenThesis