Kamruzzaman, M.Horowitz, M.Jones, K.L.Marathe, C.S.2025-07-112025-07-112021Frontiers in Endocrinology, 2021; 12(661877):661877-1-661877-101664-23921664-2392https://hdl.handle.net/2440/145883Postprandial glycemic control is an important target for optimal type 2 diabetes management, but is often difficult to achieve. The gastrointestinal tract plays a major role in modulating postprandial glycaemia in both health and diabetes. The various strategies that have been proposed to modulate gastrointestinal function, particularly by slowing gastric emptying and/or stimulating incretin hormone GLP-1, are summarized in this review.en© 2021 Kamruzzaman, Horowitz, Jones and Marathe. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.gastric emptying; type 2 diabetes; postprandial glucose (PPG); incretin hormones; GLP-1 receptor agonistHumansDiabetes Mellitus, Type 2Blood GlucoseGastric EmptyingPostprandial PeriodGlucagon-Like Peptide 1IncretinsJournal article10.3389/fendo.2021.6618772024-05-062-s2.0-85104670562574050Kamruzzaman, M. [0000-0001-5138-2182]Horowitz, M. [0000-0002-0942-0306]Jones, K.L. [0000-0002-1155-5816]