Pepper, H.Lam, H.Bloch, W.George, J.2013-01-082013-01-082012Organic Letters, 2012; 14(19):5162-51641523-70601523-7052http://hdl.handle.net/2440/74823The polycyclic polyprenylated acylphloroglucinol natural product garcibracteatone has been synthesized in four steps from phloroglucinol, using a strategy based on biosynthetic speculation. The key biomimetic transformation is a cascade of 7-endo-trig and 5-exo-trig radical cyclizations followed by a terminating aromatic substitution reaction.enCopyright © 2012 American Chemical SocietyPolycyclic CompoundsMolecular StructureModels, MolecularBiomimetic MaterialsBiomimetic total synthesis of (±)-garcibracteatoneBiomimetic total synthesis of (+/-)-garcibracteatoneJournal article002012238510.1021/ol302524q0003094384000472-s2.0-8486735579622922Bloch, W. [0000-0003-1084-1287]George, J. [0000-0002-7330-2160]