Schaaf, J.Hof, M.Mol, B.Abu-Hanna, A.Ravelli, A.2014-10-172014-10-172012American Journal of Obstetrics and Gynecology, 2012; 207(4):279.e1-279.e70002-93781097-6868http://hdl.handle.net/2440/86308Objective: The purpose of this study was to investigate the recurrence risk of preterm birth (<37 weeks' gestation) in a subsequent singleton pregnancy after a previous nulliparous preterm twin delivery. Study Design: We included 1957 women who delivered a twin gestation and a subsequent singleton pregnancy from the Netherlands Perinatal Registry. We compared the outcome of subsequent singleton pregnancy of women with a history of preterm delivery to the pregnancy outcome of women with a history of term twin delivery. Results: Preterm birth in the twin pregnancy occurred in 1075 women (55%) vs 882 women (45%) who delivered at term. The risk of subsequent spontaneous singleton preterm birth was significantly higher after preterm twin delivery (5.2% vs 0.8%; odds ratio, 6.9; 95% confidence interval, 3.1–15.2). Conclusion: Women who deliver a twin pregnancy are at greater risk for delivering prematurely in a subsequent singleton pregnancy.en© 2012 Mosby, Inc. All rights reserved.Preterm birth; recurrence risk; singleton pregnancy; twin pregnancyJournal article002013690910.1016/j.ajog.2012.07.0260003102120000182-s2.0-8486695044315248Mol, B. [0000-0001-6887-0262] [0000-0001-8337-550X]