Huang, Zhi Hua2006-12-282006-12-2819971997http://hdl.handle.net/2440/19006Bibliography: leaves 242-298.xxxiii, 298 leaves : ill. (some col.) ; 30 cm.This thesis investigates the effects of polyunsaturated fatty acids (PUFAs) on macrophage oxygen radical production. The role of fatty acid structure in the ability to stimulate the fMLP response is also examined. The mechanisms by which fatty acids induce their effects on mononuclear phagocytes are partially elucidated. The mechanisms of the biological effects of the PUFAs in terms of intracellular signalling pathway are partly defined.110976 bytesapplication/pdfenUnsaturated fatty acids.Macrophages.Chemiluminescence assay.Immune response Regulation.Thesis