Abell, A.Neffe, A.Stuart, B.Lee, H.Morton, J.Coxon, J.Nikkel, J.Robertson, L.Jones, M.Muir, M.Bickerstaffe, R.Miyamoto, S.Aitken, S.2007-08-292007-08-292006http://hdl.handle.net/2440/37598PATENT: Intellectual Property Office of New Zealand (IPONZ) number 547303. Filed 18 May 2007; accepted 31 August 2007.Disclosed are compounds that inhibit calpains of formula I wherein X is NH, O or S and all other substituents are as described in the specification. The process for their production, and use in pharmaceutical compositions and in the treatment of prophylaxis of a disease or disorder resulting from excessive calpain activity is also disclosed.enPatent002007130354730348486Abell, A. [0000-0002-0604-2629]