Verma, Paul John2006-12-282006-12-2819951995http://hdl.handle.net/2440/18729Bibliography: leaves 150-178.xxii, 178 leaves, [17] leaves of plates : ill. (chiefly col.) ; 30 cm.Investigates the potential of the zebrafish Danio rerio to provide a convenient, fecund and cost efficient piscine model for biotechnology. The technical and biological limitations of the model are identified and ways of overcoming or circumventing these limitations explored in three areas of biotechnology: transgenesis; partial genome manipulation; and, entire genome manipulatiion.305061 bytesapplication/pdfenZebra danio Genetic engineering.Zebra danio Embryos Physiology.Thesis