Cheong, K.Perry, D.Karapetis, C.Koczwara, B.2009-12-212009-12-212004Internal Medicine Journal, 2004; 34(5):234-2381444-09031445-5994http://hdl.handle.net/2440/54914The definitive version may be found at www.wiley.com<h4>Background</h4>Peripherally inserted central catheters (PICC) have been used extensively as a cost-effective and safe form of medium-term intravascular access. There are only limited data about complications of PICC lines in oncology patients despite theoretical concerns about the higher risks of complications in these patients as a result of cancer itself and cancer therapy.<h4>Aims</h4>To document the frequency and type of PICC complications in patients with solid tumours.<h4>Methods</h4>All patients with solid tumours who were treated at Flinders Medical Centre, Adelaide, South Australia, Australia between January 2000 and March 2001 were included in a retrospective review of PICC complications.<h4>Results</h4>Twenty-seven PICC lines were inserted in 17 patients; 40.7% (11/27) of PICC lines developed complications requiring early removal of the PICC. Complications encountered were sepsis (systemic and cellulitis), thrombosis, blockage and leakage. Septic complications were found at a rate of 8/1000 PICC days or 25.7% (7/27) of PICC inserted. The median dwell time was 20 days. The mean time for a complication to occur was 27.5 days.<h4>Conclusions</h4>The present study demonstrates a high rate of complications, which is higher than the complication rates reported in studies of non-oncology patients. PICC lines should be used with caution in patients with solid tumours. Prospective studies of the factors influencing the incidence of complications might be warranted.enHumansNeoplasmsThrombophlebitisCritical IllnessAntineoplastic AgentsCatheterization, Central VenousCatheterization, PeripheralRetrospective StudiesCatheters, IndwellingFemaleMaleInfectionsJournal article002009198210.1111/j.1444-0903.2004.00447.x0002214229000042-s2.0-294256832637993