Kelly, J.M.Hynes, M.J.2014-10-062014-10-061982Microbiology, 1982; 128(1):23-281350-08721465-2080http://hdl.handle.net/2440/85859The regulation of NADP-linked isocitrate dehydrogenase (NADP-IDH) has been studied in wild-type and mutant strains of Aspergillus nidulans. In the wild-type strain studied, the levels of NADP-IDH vary in a similar way to those of acetamidase, acetyl-CoA synthase, isocitrate lyase and malate synthase under all growth conditions used. Similarly,foc mutants, which are altered in the regulation of these enzymes of acetate utilization, are affected in NADP-IDH levels in a parallel fashion, as are cre mutants, which show altered carbon catabolite repression of this group of enzymes. Possible functions of the NADP-IDH enzyme are considered.en© 1982 SGMJournal article003000943910.1099/00221287-128-1-23107695