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https://hdl.handle.net/2440/61543
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Type: | Journal article |
Title: | Innate Immunity |
Author: | Ooi, E. Psaltis, A. Witterick, I. Wormald, P. |
Citation: | Otolaryngologic Clinics of North America, 2010; 43(3):473-487 |
Publisher: | W B Saunders Co |
Issue Date: | 2010 |
ISSN: | 0030-6665 1557-8259 |
Statement of Responsibility: | Eng H. Ooi, Alkis J. Psaltis, Ian J. Witterick and Peter-John Wormald |
Abstract: | Innate immunity is an exciting area of research in rhinology because emerging evidence suggests that abnormal local immune responses, rather than pathogen-specific adaptive immunity, may play a more important role in the pathogenesis of chronic rhinosinusitis (CRS). This article reviews important recent research regarding the innate immune system and CRS, with particular focus on the role of pattern recognition receptors, antimicrobial peptides and biofilms, epithelial ciliary function, cystic fibrosis, and cigarette smoking, and on areas for future research and therapy. |
Keywords: | Innate immunity Rhinosinusitis Biofilms Cigarette smoke Toll-like receptors Cystic fibrosis |
Rights: | Copyright © 2010 Elsevier Inc. All rights reserved. |
DOI: | 10.1016/j.otc.2010.02.020 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/623170/description#description |
Published version: | http://dx.doi.org/10.1016/j.otc.2010.02.020 |
Appears in Collections: | Aurora harvest Surgery publications |
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