Adelaide Research & Scholarship
Adelaide Research & Scholarship (AR&S) is the University of Adelaide’s digital repository. AR&S provides a platform for the collection, organisation, access and preservation of the research and scholarly outputs of the University community in digital formats, as well as digital management of information in physical formats.
University of Adelaide higher degree by research theses are deposited into the AR&S Theses community as part of the final thesis lodgement process.
AR&S also serves as the home of the digital collections of University Library Archives and Special Collections. Items include digitized representations of physical items, such as photographs and full texts, and digital-born materials, allowing worldwide access to our heritage and research collections.
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Recent Submissions
Assessing Seminal Fluid Interaction with Female Reproductive Tract Tissues: In Vivo and In Vitro Models for Mouse
(Humana Press, 2025) Chan, H.Y.; Schjenken, J.E.; Sharkey, D.J.; Robertson, S.A.; Álvarez-Rodríguez, M.
After intromission of seminal fluid at mating in mammals, the seminal fluid interacts with the lining of the female reproductive tract and elicits a female immune response. This response is triggered by signals in seminal fluid (carried by both the sperm and seminal plasma components) that bind receptors on female tract epithelial cells, causing a change in their transcriptional program to upregulate expression of pro-inflammatory cytokines and chemokines. The ensuing leukocyte recruitment and immune activation facilitates conception, embryo development, and progression of pregnancy. In this chapter, we report methods for evaluating effects of seminal fluid and its components (seminal plasma and sperm) on the female reproductive tract immune response in mice.
Seminal Fluid Interaction with Female Reproductive Tract Epithelial Cells: In Vitro Models for Human
(Humana Press, 2025) Sharkey, D.J.; Lyons, H.E.; Chan, H.Y.; Robertson, S.A.; Álvarez-Rodríguez, M.
Seminal fluid introduced into the female reproductive tract following unprotected coitus initiates an inflammation-like response in the cervical tissues that stimulates immune tolerance to male seminal fluid alloantigens and promotes immune adaptation for pregnancy. This response commences when seminal fluid factors induce genes encoding pro-inflammatory cytokines and chemokines including CSF2, IL6, and CXCL8, that in turn cause recruitment of macrophages, dendritic cells, and T cells into the epithelial and stromal layers. Various signaling agents present in seminal plasma provoke the post-coital pro-inflammatory activation and regulate the quality of immune response. However, the factors identified to date do not account for all the biological activity within seminal fluid, implying sperm-associated factors may also contribute. In this chapter, we report methods for evaluating the effects of human seminal fluid components (seminal plasma and sperm) on the female reproductive tract immune response in primary and immortalized ectocervical epithelial cells in vitro.
'You don’t really want to hide it...': exploring young working-class men’s mental health literacy
(Taylor and Francis Group, 2024) Stahl, G.; Adams, B.; Wang, J.
Australia’s National Men’s Health Strategy 2020–2030 considers men from socio-economically disadvantaged backgrounds to be a priority population and foregrounds the importance of initiatives focused on empowerment. This article seeks to explore young working-class men’s experiences with mental health in their years immediately following compulsory schooling. Drawing data from a larger study, we explore five young men who openly discussed their mental health. The analysis focuses on where they struggled, how they struggled and what self-care they enacted. Adopting a health literacy framework, we highlight two broad themes: closing yourself off and opening up. While historically working-class manhood has been centred around stoicism and a reluctance to admitting vulnerability, these case studies suggest that the identity work around masculinities and mental health may be experiencing change.
A Likelihood-Free Bayesian Framework for Model-Based Damage Identification Using Guided Waves
(Springer Nature, 2025) Zeng, Z.; Ng, C.T.; 1st International Conference on Engineering Structures (ICES) (8 Nov 2024 - 11 Nov 2024 : Guangzhou, China)
Guided wave (GW) has been widely used in engineering structures for structural health monitoring (SHM) because of its capability of long propagation and high sensitivity to local defects. Bayesian methods have been commonly employed to enhance the reliability of GW-based damage identification. In addition to more accurate detection, the corresponding uncertainties within unknown parameters can be quantified by assessing the posterior distributions. However, applications of most existing Bayesian frameworks require a proper likelihood assumption, which tends to restrict the applicability when dealing with a complex or high-dimensional problem. Conversely, approximate Bayesian computation (ABC), a likelihood-free method while still obeying the Bayes theorem, provides a more straightforward alternative to solving the Bayesian inference problem. The posterior distributions of unknowns are estimated using a distance function to assess the similarity between simulation and measurement. Summary statistics, such as signal processing techniques in GW, can also be used to pre-process datasets to enhance comparison sensitivity. In these cases, no explicit likelihood function is needed for posterior estimation. In this paper, A GW-based damage identification framework is proposed using ABC. An experiment of multiple cracks in the isotropic metal rod is carried out. The measurement is used in the proposed ABC framework to detect the corresponding damage locations and sizes. Extensive studies are conducted to evaluate the ABC performance. Recommendations are provided based on identification results. Additionally, this research provides a further understanding of ABC framework development for GW-based SHM.
A parametric investigation of methane jets in direct-injection compression-ignition conditions
(Elsevier, 2023) Wan, Q.; Zhai, G.; Wang, C.; Yuen, A.C.Y.; Medwell, P.R.; Kook, S.; Yeoh, G.H.; Chan, Q.N.
This work investigated the effects of ambient and injection conditions on the autoignition, flame evolution and combustion characteristics of the natural gas jets at direct-injection (DI) compression-ignition (CI) conditions. Methane (CH4, as a natural gas surrogate) was directly injected into an optically accessible constant-volume combustion chamber (CVCC). For the experiments, the ambient gas density within the CVCC was fixed at 24 kgm−3, but other ambient conditions were varied, including ambient gas temperature (1060–1200K) and ambient oxygen concentration (10–21 vol.%). The effects of injection pressure (10–20MPa reservoir pressure) were also assessed at a fixed ambient temperature and ambient oxygen conditions of 1200K and 21 vol.%, respectively. High-speed schlieren imaging, heat release rate analysis and flame luminosity measurement were applied to the CH4 jet flames. The results show that the ignition delay decreases with increasing ambient temperature or ambient oxygen concentration but does not display an apparent trend with changing injection pressure. Optical images reveal that the CH4 jet combustion typically starts from a localised kernel before propagating downstream of the jet volume in most cases, other than the lower ambient oxygen concentration case. The optical results also reveal that after ignition, the CH4 jet flame recesses back towards the nozzle before stabilising at a lift-off distance. The jet becomes more lifted with a decreasing ambient temperature, a reducing ambient oxygen concentration, and an increasing reservoir pressure. The results also reveal that the heat release rate and flame luminosity profiles roughly correspond to the ignition and combustion characteristics of the CH4 jet flames.