Adelaide Research & Scholarship

Adelaide Research & Scholarship (AR&S) is the University of Adelaide’s digital repository. AR&S provides a platform for the collection, organisation, access and preservation of the research and scholarly outputs of the University community in digital formats, as well as digital management of information in physical formats.

University of Adelaide higher degree by research theses are deposited into the AR&S Theses community as part of the final thesis lodgement process.

AR&S also serves as the home of the digital collections of University Library Archives and Special Collections. Items include digitized representations of physical items, such as photographs and full texts, and digital-born materials, allowing worldwide access to our heritage and research collections.

Are you a University of Adelaide researcher who would like your publications in AR&S? See our support page.

Contact us. Please email Library Discovery.

 

Communities in Adelaide Research & Scholarship

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Recent Submissions

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Trends in Treatment Strategies and Perioperative Outcomes for Complex Abdominal Aortic Aneurysms: A VASCUNET Report
(Elsevier, 2025) Meuli, L.; Gavali, H.; Budtz-Lilly, J.; Khashram, M.; Lattmann, T.; Lopez-Espada, C.; Møller, C.M.; McMillan, N.; Ribeiro, T.F.; Venermo, M.; Mani, K.
Objective: To examine trends in treatment strategies and perioperative outcomes for intact and ruptured complex abdominal aortic aneurysms (cAAA) across seven countries. Design: Multinational, registry-based observational study within the VASCUNET framework. Methods: This study used aggregated data from vascular registries in Australia, Denmark, Finland, New Zealand, Portugal, Sweden, and Switzerland. Patients treated with open repair (OR) and fenestrated (or branched) endovascular aortic repair (F/BEVAR) for intact and ruptured cAAA between 2018-2022 were included. The primary outcome was perioperative mortality (30-day or in-hospital). Weighted perioperative mortality rates with 95% confidence intervals (95%-CI) were calculated and variations in treatment practices and outcomes were assessed. Results: 3344 patients treated for intact cAAA, and 547 patients treated for ruptured cAAA were included. An overall increase in the use of F/BEVAR for intact cAAA was observed, rising from 50% in 2018 to 54% in 2022, with Denmark showing the largest rise, from 33% to 71%. The highest F/BEVAR rate was seen in Australia at 68%, the lowest in Switzerland at 25%. In contrast, OR was the predominant treatment for ruptured cAAA, accounting for 94% of all procedures without a clear trend. The overall perioperative mortality for intact cAAA decreased from 5.2% (95%-CI: 3.3-7.0%) in 2018 to 2.4% (1.3-3.5%) in 2022, though the trend was not statistically significant (p=.09). No time trend was observed in the perioperative mortality for ruptured cAAA, with an overall mortality rate of 35.6%. Complication rates, including myocardial infarction, acute kidney failure, and respiratory failure were more frequent in OR patients. Conclusion: While the use of F/BEVAR for elective cAAA repair has increased and mortality rates show a declining trend, the treatment of ruptured cAAA continues to rely predominantly on OR, with high perioperative mortality rates. These findings highlight the need for ongoing advancements in endovascular technologies for ruptured cAAA repairs.
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What Is Decoupling and Where Is Our World Headed?
(Springer Nature, 2025) Gao, M.; O'Connor, J.; Xie, B.; Butcher, J.; Gao, M.; O'Connor, J.; Xie, B.; Butcher, J.D.
This introductory chapter examines ‘decoupling’ in the context of recent U.S. and allied efforts to reduce economic and technological reliance on China. Decoupling is a strategy to uphold U.S. hegemony by reconfiguring global trade to reduce economic and technological dependence on China amidst rising geopolitical tensions, limiting Chinese access to advanced sectors, and signalling a shift away from globalisation. Highlighting the main arguments presented in the book, this chapter envisions an alternative future addressing various topics, apart from trade, finance and geopolitics, from environmental challenges and philosophies of coexistence to the promotion of greater economic openness and engagement with the Global South, advocating for a new global order centred on peace, cooperation, and shared prosperity.
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Grassroots Perceptions of Australia in China During Diplomatic Tensions: A Lens Through “We-Media” Framing
(Palgrave Macmillan, 2023) Butcher, J.; Gao, M.; O'Connor, J.; Xie, B.; Butcher, J.
Chinese and Australians often view themselves as “worlds apart”. This view has only intensified since the deterioration of diplomatic relations. Views of China are well known in Australia, with China depicted and perceived increasingly negatively. However, perceptions of Australia in China remain largely unexplored. This chapter conducts a qualitative frame analysis of Chinese language “we-media” contents through four media frames: conflict, human interest, economic consequences and responsibility to explore how Australia has been portrayed and perceived at the grassroots level in China. This chapter aims to inform a non-Chinese-speaking audience regarding the diversity of views communicated about Australia in China at the grassroots level and promote mutual understanding for a shared future.
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ASO Visual Abstract: Compliance and Toxicity of Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer: A Systematic Review and Network Meta-analysis
(Springer, 2025) Seow, W.; Murshed, I.; Bunjo, Z.; Bedrikovetski, S.; Stone, J.; Sammour, T.
Across all treatment strategies, induction total neoadjuvant therapy (iTNT) had higher radiation-related gastrointestinal toxicities and postoperative diarrhea; consolidation total neoadjuvant therapy (cTNT) had higher vomiting and lymphopenia rates. While no treatment strategy was superior in chemotherapy compliance, radiotherapy compliance was ranked highest in cTNT.
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Strategies for the optimisation of troublesome peptide nucleic acid (PNA) sequences
(Royal Society of Chemistry, 2025) Watson, E.E.
Through the use of a pseudo-peptidic backbone, peptide nucleic acids (PNA) mimic the functionality of native nucleic acids while enjoying improved binding affinity and metabolic stability. However, many aspects of the application of PNA to biological and medicinal settings still requires sequence specific optimisation. This review highlights key areas for refinement, including synthesis, tuning of physical properties, cell permeability and analysis, including common strategies for the pracitioner to apply in each area.