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PreviewIssue DateTitleAuthor(s)
2013Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-c and extracellular cyclic guanosine 3′,5′-monophosphateCastro, J.; Harrington, A.; Hughes, P.; Martin, C.; Ge, P.; Shea, C.; Jin, H.; Jacobson, S.; Hannig, G.; Mann, E.; Cohen, M.; MacDougall, J.; Lavins, B.; Kurtz, C.; Silos-Santiago, I.; Johnston, J.; Blackshaw, L.; Brierley, S.
2019Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in femalesJackson, M.R.; Loring, K.E.; Homan, C.C.; Thai, H.N.; Määttänen, L.; Arvio, M.; Jarvela, I.; Shaw, M.; Gardner, A.; Gecz, J.; Shoubridge, C.
2019Activation of pruritogenic TGR5, MRGPRA3, and MRGPRC11 on colon-innervating afferents induces visceral hypersensitivityCastro, J.; Harrington, A.M.; Lieu, T.; Garcia Caraballo, S.; Maddern, J.; Schober, G.; O'Donnell, T.; Grundy, L.; Lumsden, A.L.; Miller, P.E.; Ghetti, A.; Steinhoff, M.S.; Poole, D.P.; Dong, X.; Chang, L.; Bunnett, N.W.; Brierley, S.M.
2019Alpha-Blockers as colorectal cancer chemopreventive: findings from a case-control study, human cell cultures, and in vivo preclinical testingSuzuki, N.; Niikura, R.; Ihara, S.; Hikiba, Y.; Kinoshita, H.; Higashishima, N.; Hayakawa, Y.; Yamada, A.; Hirata, Y.; Nakata, R.; Okamoto, M.; Sano, M.; Kushiyama, A.; Ichinose, M.; Woods, S.L.; Worthley, D.; Iwamoto, Y.; Koike, K.
2014Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cellsNievergall, E.; Ramshaw, H.; Yong, A.; Biondo, M.; Busfield, S.; Vairo, G.; Lopez, A.; Hughes, T.; White, D.; Hiwase, D.
2012Glucokinase links Kruppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver diseaseBechmann, L.; Gastaldelli, A.; Vetter, D.; Patman, G.; Pascoe, L.; Hannivoort, R.; Lee, U.; Fiel, I.; Munoz, U.; Ciociaro, D.; Lee, Y.; Buzzigoli, E.; Miele, L.; Hui, K.; Bugianesi, E.; Burt, A.; Day, C.; Mari, A.; Agius, L.; Walker, M.; et al.
2015DNA-PK—A Candidate Driver of Hepatocarcinogenesis and Tissue Biomarker That Predicts Response to Treatment and SurvivalCornell, L.; Munck, J.; Alsinet, C.; Villanueva, A.; Ogle, L.; Willoughby, C.; Televantou, D.; Thomas, H.; Jackson, J.; Burt, A.; Newell, D.; Rose, J.; Manas, D.; Shapiro, G.; Curtin, N.; Reeves, H.
2013Sensory neuro-immune interactions differ between Irritable Bowel Syndrome subtypesHughes, P.; Harrington, A.; Castro Kraftchenko, J.; Liebregts, T.; Adam, B.; Grasby, D.; Isaacs, N.; Maldeniya, M.; Martin, C.; Persson, J.; Andrews, J.; Holtmann, G.; Blackshaw, L.; Brierley, S.
2015Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatmentAdomako, A.; Calvo, V.; Biran, N.; Osman, K.; Chari, A.; Paton, J.; Paton, A.; Moore, K.; Schewe, D.; Aguirre-Ghiso, J.
2004Cellular mucosal defense is attenuated with chronicity of Helicobacter pylori infectionMatthews, G.; Tivey, D.; Cummins, A.; Butler, R.