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PreviewIssue DateTitleAuthor(s)
2015Evaluation of enzyme dose and dose-frequency in ameliorating substrate accumulation in MPS IIIA Huntaway dog brainKing, B.; Marshall, N.; Beard, H.; Hassiotis, S.; Trim, P.; Snel, M.; Rozaklis, T.; Jolly, R.; Hopwood, J.; Hemsley, K.
2010Lessons learnt from animal models: pathophysiology of neuropathic lysosomal storage disordersHemsley, K.; Hopwood, J.
2008Behavioural characterisation of the alpha-mannosidosis guinea pigRobinson, A.; Crawley, A.; Auclair, D.; Weston, P.; Hirte, C.; Hemsley, K.; Hopwood, J.
2011Emerging therapies for neurodegenerative lysosomal storage disorders - from concept to realityHemsley, K.; Hopwood, J.
2004Intracerebral injection of sulfamidase delays neuropathology in murine MPS-IIIASavas, P.; Hemsley, K.; Hopwood, J.
2004In vitro characterization of genetically modified embryonic stem cells as a therapy for murine mucopolysaccharidosis type IIIALau, A.; Hemsley, K.; Meedeniya, A.; Hopwood, J.
2007Functional correction of CNS lesions in an MPS-IIIA mouse model by intracerebral AAV-mediated delivery of sulfamidase and SUMF1 genesFraldi, A.; Hemsley, K.; Crawley, A.; Lombardi, A.; Lau, A.; Sutherland, L.; Auricchio, A.; Ballabio, A.; Hopwood, J.
2005Development of motor deficits in a murine model of mucopolysaccharidosis type IIIA (MPS-IIIA)Hemsley, K.; Hopwood, J.
2005Survival and engraftment of mouse embryonic stem cell-derived implants in the guinea pig brainRobinson, A.; Meedeniya, A.; Hemsley, K.; Auclair, D.; Crawley, A.; Hopwood, J.
2009Delivery of recombinant proteins via the cerebrospinal fluid as a therapy option for neurodegenerative lysosomal storage diseasesHemsley, K.; Hopwood, J.