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Type: Journal article
Title: Effect of packing on nasal mucosa of sheep
Author: Shaw, C.
Dymock, R.
Cowin, A.
Wormald, P.
Citation: Journal of Laryngology and Otology, 2000; 114(7):506-509
Publisher: Headley Brothers Ltd
Issue Date: 2000
ISSN: 0022-2151
Statement of
Chi-kee Leslie Shaw, Robert B. Dymock, Allison Cowin and Peter-John Wormald
Abstract: The effects of packing with ribbon gauze and neuropatties on the nasal mucosa was assessed using sheep as an animal model. Fourteen sheep either underwent ribbon gauze or neuropattie nasal packing. Trauma to nasal mucosa caused by ribbon gauze and neuropatties was compared to mucosa on the lateral aspect of the middle turbinate which was not in contact with any packing. This tissue was used as a control. Ribbon gauze packing resulted in significant loss of 68 per cent of the ciliated surface of the mucosa when compared with the control group with a 15 per cent loss of ciliated surface (p < 0.005). Neuropattie packing also resulted in significant loss of 50 per cent of the ciliated surface of the mucosa when compared with the control group (p < 0.005). There was no significant difference in loss of ciliated mucosa in the specimens packed with ribbon gauze or neuropatties (p = 0.25). Nasal packing results in a significant mucosal injury with loss of cilia. This may influence the mucociliary clearance of the nose in the post-operative healing phase. Pre-operative nasal packing should be used circumspectly and if possible avoided.
Keywords: Nose
Nasal Mucosa
Otorhinolaryngologic Surgical Procedures
Occlusive Dressings
Provenance: Published online by Cambridge University Press 08 Mar 2006
Rights: Copyright © Royal Society of Medicine Press Limited 2000
DOI: 10.1258/0022215001906246
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Appears in Collections:Aurora harvest 7
Surgery publications

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