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Type: Journal article
Title: Microvascular histopathology in head and neck oncology
Author: Stavrianos, S.
McLean, N.
Fellows, S.
Hodgkinson, P.
Kostaki, A.
Kelly, C.
Soames, J.
Citation: Journal of Plastic, Reconstructive & Aesthetic Surgery, 2003; 56(2):140-144
Publisher: Print Edition - Churchill Livingstone
Issue Date: 2003
ISSN: 1748-6815
Abstract: A histological study of both recipient and flap vessels was performed in 30 patients with head and neck cancer, and relevant preoperative risk factors were assessed. A total of 35 free flaps were transferred in 30 patients; 16 patients had preoperative radiotherapy, 13 were smokers, eight had hypertension and six had peripheral vascular disease. No significant venous pathology was found in either the flap or the neck veins. However, over two-thirds of the neck arteries and one-half of the flap arteries were found to have microscopic arterial pathology. The only pre-existing factor significantly influencing vessel pathology was hypertension (P=0.007). All flaps survived, although in two there was some loss of the skin paddle. This study reveals that the majority of patients undergoing microsurgery in the head and neck region have pre-existing arterial damage in both the flap and the recipient arteries, but this does not have a significant effect on the overall patency of the microvascular anastomoses.
Keywords: Microcirculation; Surgical Flaps; Humans; Head and Neck Neoplasms; Neoplasm Recurrence, Local; Postoperative Complications; Treatment Outcome; Preoperative Care; Anastomosis, Surgical; Reconstructive Surgical Procedures; Risk Factors; Prospective Studies; Time Factors; Adult; Aged; Aged, 80 and over; Middle Aged; Female; Male
RMID: 0020030554
DOI: 10.1016/S0007-1226(03)00024-9
Appears in Collections:Surgery publications

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