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https://hdl.handle.net/2440/10545
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Type: | Journal article |
Title: | Microvascular histopathology in head and neck oncology |
Author: | Stavrianos, S. McLean, N. Fellows, S. Hodgkinson, P. Kostaki, A. Kelly, C. Soames, J. |
Citation: | Journal of Plastic, Reconstructive and Aesthetic Surgery, 2003; 56(2):140-144 |
Publisher: | Print Edition - Churchill Livingstone |
Issue Date: | 2003 |
ISSN: | 1748-6815 0007-1226 |
Abstract: | A histological study of both recipient and flap vessels was performed in 30 patients with head and neck cancer, and relevant preoperative risk factors were assessed. A total of 35 free flaps were transferred in 30 patients; 16 patients had preoperative radiotherapy, 13 were smokers, eight had hypertension and six had peripheral vascular disease. No significant venous pathology was found in either the flap or the neck veins. However, over two-thirds of the neck arteries and one-half of the flap arteries were found to have microscopic arterial pathology. The only pre-existing factor significantly influencing vessel pathology was hypertension (P=0.007). All flaps survived, although in two there was some loss of the skin paddle. This study reveals that the majority of patients undergoing microsurgery in the head and neck region have pre-existing arterial damage in both the flap and the recipient arteries, but this does not have a significant effect on the overall patency of the microvascular anastomoses. |
Keywords: | Microcirculation Surgical Flaps Humans Head and Neck Neoplasms Neoplasm Recurrence, Local Postoperative Complications Treatment Outcome Preoperative Care Anastomosis, Surgical Risk Factors Prospective Studies Time Factors Adult Aged Aged, 80 and over Middle Aged Female Male Plastic Surgery Procedures |
DOI: | 10.1016/S0007-1226(03)00024-9 |
Published version: | http://dx.doi.org/10.1016/s0007-1226(03)00024-9 |
Appears in Collections: | Aurora harvest 2 Surgery publications |
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