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Type: Journal article
Title: Factors influencing the development of wound infection following free-flap reconstruction for intra-oral cancer
Author: Cloke, D.
Green, J.
Khan, A.
Hodgkinson, P.
McLean, N.
Citation: Journal of Plastic, Reconstructive & Aesthetic Surgery, 2004; 57(7):556-560
Publisher: Print Edition - Churchill Livingstone
Issue Date: 2004
ISSN: 1748-6815
Abstract: Wound infection following tissue transfer in head and neck oncology is common. Factors known to be associated with infective complications include blood transfusion, pre-operative radiotherapy, duration of surgery, duration of pre-operative stay and a history of smoking. The present study specifically examined 100 consecutive patients on a standard antibiotic protocol undergoing free flap reconstruction following resection of cancers of the oral cavity or oropharynx. Despite prophylactic antibiotics, 21 patients developed a head and neck wound infection. No statistically significant association was found between infective wound complications and a history of smoking, pre-operative radiotherapy or chemotherapy, length of pre-operative hospital stay, duration of surgery, or number of units of blood transfused. We conclude that, in this group of patients, wound infection is a common and difficult problem, but with no statistically significant association with any of the variables studied.
Keywords: Surgical Flaps; Humans; Staphylococcal Infections; Surgical Wound Infection; Mouth Neoplasms; Cefuroxime; Metronidazole; Drug Therapy, Combination; Premedication; Reconstructive Surgical Procedures; Prospective Studies; Adult; Aged; Aged, 80 and over; Middle Aged; Female; Male
RMID: 0020041945
DOI: 10.1016/j.bjps.2004.04.006
Appears in Collections:Surgery publications

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