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|Title:||Malignant tumours of the minor salivary glands - a 20 year review|
|Citation:||Journal of Plastic, Reconstructive & Aesthetic Surgery, 2004; 57(7):624-631|
|Publisher:||Print Edition - Churchill Livingstone|
|Abstract:||The UK incidence of malignant disease of the minor salivary glands is only 0.6 per million per year. The tumours have a varied histology, can present in any age group and are frequently advanced if located in the sinonasal cavities. In a 20-year review of 21 patients treated for minor salivary gland malignancy in a single institution, it was found that mucoepidermoid tumours were more common in the oral cavity and adenoid cystic carcinomas in the sinonasal tract (p = 0.002). Outcome was variable with sinonasal and adenoid cystic carcinoma having a poorer outcome. Kaplan-Meier curves showed that oral tumours had a higher probability of long term survival. Radical surgery with reconstruction and post-operative adjuvant radiotherapy was effective in achieving loco-regional control. There were no local recurrences within 5 years and three after 5 years. Five patients developed metastatic disease within 10 years and a further two after 10 years. Late recurrences occurred and survival was mainly determined by the presence of systemic disease.|
|Keywords:||Salivary Glands, Minor; Humans; Salivary Gland Neoplasms; Tomography, X-Ray Computed; Magnetic Resonance Imaging; Disease-Free Survival; Combined Modality Therapy; Follow-Up Studies; Adult; Aged; Aged, 80 and over; Middle Aged; Female; Male|
|Appears in Collections:||Surgery publications|
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