Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/10550
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Type: Journal article
Title: Malignant tumours of the minor salivary glands - a 20 year review
Author: Strick, M.
Kelly, C.
Soames, J.
McLean, N.
Citation: Journal of Plastic, Reconstructive & Aesthetic Surgery, 2004; 57(7):624-631
Publisher: Print Edition - Churchill Livingstone
Issue Date: 2004
ISSN: 1748-6815
0007-1226
Abstract: The UK incidence of malignant disease of the minor salivary glands is only 0.6 per million per year. The tumours have a varied histology, can present in any age group and are frequently advanced if located in the sinonasal cavities. In a 20-year review of 21 patients treated for minor salivary gland malignancy in a single institution, it was found that mucoepidermoid tumours were more common in the oral cavity and adenoid cystic carcinomas in the sinonasal tract (p = 0.002). Outcome was variable with sinonasal and adenoid cystic carcinoma having a poorer outcome. Kaplan-Meier curves showed that oral tumours had a higher probability of long term survival. Radical surgery with reconstruction and post-operative adjuvant radiotherapy was effective in achieving loco-regional control. There were no local recurrences within 5 years and three after 5 years. Five patients developed metastatic disease within 10 years and a further two after 10 years. Late recurrences occurred and survival was mainly determined by the presence of systemic disease.
Keywords: Salivary Glands, Minor; Humans; Salivary Gland Neoplasms; Tomography, X-Ray Computed; Magnetic Resonance Imaging; Disease-Free Survival; Combined Modality Therapy; Follow-Up Studies; Adult; Aged; Aged, 80 and over; Middle Aged; Female; Male
RMID: 0020041944
DOI: 10.1016/j.bjps.2004.04.017
Appears in Collections:Surgery publications

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