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Type: Journal article
Title: Craniopharyngioma: a review of long-term visual outcome
Author: Chen, C.
Okera, S.
Davies, P.
Selva-Nayagam, D.
Crompton, J.
Citation: Clinical and Experimental Ophthalmology, 2003; 31(3):220-228
Publisher: Blackwell Publishing Asia
Issue Date: 2003
ISSN: 1442-6404
Abstract: PURPOSE:To assess the clinical presentation and long-term visual outcome in a series of patients with craniopharyn-gioma. METHODS:Retrospective case review. RESULTS:Thirty-six patients were reviewed, comprising 19 female patients and 17 male patients. The age range was 2-77 years with a bimodal distribution of 17 children (mean age 10 years) and 19 adults (mean age 47 years). Blurred vision was the most common visual complaint (23 cases, 64%) and headache the most frequent systemic complaint (19 cases, 53%). The average duration of systemic symptoms was 45 weeks compared to 10 weeks for visual symptoms. Deficits in visual acuity occurred in 13 patients (36%) and showed no significant change from initial presentation to final review. Sixteen patients (44%) had bitemporal hemianopia on presentation and pleomorphism (change from one type of visual field defect to another) occurred in 11 patients. Recurrence of tumour occurred in 15 patients (42%) and was more likely in children (59%) than adults (26%). The mean time period to recurrence was 7 years. The average follow-up period for all cases was 10 years. CONCLUSION:Patients with craniopharyngioma generally present late, and the visual symptoms are often preceded by a long history of systemic symptoms. Children are more likely to present with systemic symptoms than adults. Visual field pleomorphism is a feature of craniopharyngioma and occurred in one-third of the patients. Local recurrence is common. Although magnetic resonance imaging is the recommended means of follow up, regular neuro-ophthalmic review is useful in the early detection of anterior visual pathway compression by recurrent tumour.
Keywords: Fundus Oculi
Pituitary Neoplasms
Neoplasm Recurrence, Local
Vision Disorders
Postoperative Complications
Tomography, X-Ray Computed
Magnetic Resonance Imaging
Treatment Outcome
Retrospective Studies
Follow-Up Studies
Visual Acuity
Visual Fields
Middle Aged
Child, Preschool
Vision, Ocular
DOI: 10.1046/j.1442-9071.2003.00648.x
Appears in Collections:Aurora harvest 7
Surgery publications

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