Please use this identifier to cite or link to this item:
Scopus Web of ScienceĀ® Altmetric
Type: Journal article
Title: Antral compensation after proximal gastric vagotomy
Author: Anvari, M.
Myers, J.
Malbert, C.
Horowitz, M.
Dent, J.
Jamieson, G.
Citation: Journal of Gastrointestinal Surgery, 2000; 4(5):526-530
Publisher: Quality Medical Publishing Inc
Issue Date: 2000
ISSN: 1091-255X
Statement of
Anvari, Mehran ; Myers, Jenny ; Malbert, Charles ; Horowitz, Michael ; Dent, John ; Jamieson, Glyn
Abstract: Proximal gastric vagotomy (PGV) has little impact on the normal pattern of solid gastric emptying, despite denervation of the proximal two thirds of the stomach and loss of the proximal gastric pump. In four healthy volunteers and four patients with PGV, we investigated the possible compensatory mechanisms that may come into play after proximal denervation of the stomach. We measured antropyloroduodenal motility with a 10-lumen sleeve/side-hole catheter for 180 minutes after ingestion of a dual-isotope radiolabeled mixed liquid/solid meal. Patients with PGV exhibited faster liquid emptying, but the rate of solid emptying was similar to that in healthy volunteers. The frequency of propagated antropyloric pressure wave was similar between the two groups, but patients with PGV exhibited less isolated pressure waves in the proximal antrum. The amplitude and duration of pressure waves recorded in the distal antrum were significantly increased in the PGV patients as compared to healthy volunteers. Although the pattern of propagated antral contractions and solid gastric emptying remains unchanged after PGV, there is an increase in the amplitude and duration of distal antral contractions, which may compensate for loss of proximal gastric pumping mechanisms.
Keywords: Pyloric Antrum
Vagotomy, Proximal Gastric
Postoperative Period
Gastrointestinal Motility
Gastric Emptying
Middle Aged
DOI: 10.1016/S1091-255X(00)80096-7
Appears in Collections:Aurora harvest 2
Surgery publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.