Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/116168
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Type: | Conference paper |
Title: | Measurements of vitamin B12 in human blood serum using resonance Raman spectroscopy |
Author: | Tsiminis, G. Schartner, E. Brooks, J. Hutchinson, M. |
Citation: | Proceedings of SPIE, 2016 / Hutchinson, M., Goldys, E. (ed./s), vol.10013, pp.100130M-1-100130M-4 |
Publisher: | SPIE |
Issue Date: | 2016 |
Series/Report no.: | Proceedings of SPIE |
ISBN: | 9781510604346 |
ISSN: | 0277-786X 1996-756X |
Conference Name: | SPIE BioPhotonics Australasia (17 Oct 2016 - 19 Oct 2016 : Adelaide, Australia) |
Editor: | Hutchinson, M. Goldys, E. |
Statement of Responsibility: | G. Tsiminis, E. P. Schartner, J. L. Brooks, M. R. Hutchinson |
Abstract: | Vitamin B12 (cobalamin and its derivatives) deficiency has been identified as a potential modifiable risk factor for dementia and Alzheimer’s disease. Chronic deficiency of vitamin B12 has been significantly associated with an increased risk of cognitive decline. An effective and efficient method for measuring vitamin B12 concentration in human blood would enable ongoing tracking and assessment of this potential modifiable risk factor. In this work we present an optical sensor based on resonance Raman spectroscopy for rapid measurements of vitamin B12 in human blood serum. The measurement takes less than a minute and requires minimum preparation (centrifuging) of the collected blood samples. |
Keywords: | Raman spectroscopy; vitamin B12; optical spectroscopy; dementia; Alzheimer’s disease; cognitive decline |
Rights: | © 2016 SPIE |
DOI: | 10.1117/12.2244620 |
Published version: | http://dx.doi.org/10.1117/12.2244620 |
Appears in Collections: | Aurora harvest 3 Physics publications |
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hdl_116168.pdf | Published version | 624.11 kB | Adobe PDF | View/Open |
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