Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/11799
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Type: Journal article
Title: Postnatal growth and circulating ACTH and cortisol concentrations during the first month of life in cloned lambs
Author: Edwards, L.
Peura, T.
Hartwich, K.
Rudiger, S.
McMillen, I.
Walker, S.
Citation: Endocrinology, 2002; 143(9):3699-3702
Publisher: Endocrine Soc
Issue Date: 2002
ISSN: 0013-7227
1945-7170
Abstract: Recent studies have indicated that there is a decrease in perinatal survival of apparently normal animals produced by somatic-cell nuclear transfer. Here we report that the cortisol and adrenocorticotrophic hormone (ACTH) profiles of cloned lambs in the first 4 weeks of life are significantly different to that of control lambs. The growth of cloned lambs however was not different to controls. These findings demonstrate that endocrine development may be altered in apparently "normal" clones.
Keywords: Animals; Animals, Newborn; Sheep; Hydrocortisone; Embryo Transfer; Cloning, Organism; Aging; Pregnancy; Female; Adrenocorticotropic Hormone; Nuclear Transfer Techniques
RMID: 0020020716
DOI: 10.1210/en.2002-220500
Appears in Collections:Physiology publications

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