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|Title:||Neutrophil-lymphocyte ratio - a simple, accessible measure of inflammation, morbidity and prognosis in psychiatric disorders?|
|Citation:||Australas Psychiatry, 2020; 28(4):454-458|
|Zlatan Zulfic, Cynthia Shannon Weickert, Thomas W Weickert, Dennis Liu, Nicholas Myles, Cherrie Galletly|
|Abstract:||OBJECTIVE: A narrative review to describe the utility of the neutrophil-lymphocyte ratio (NLR) as an inflammatory marker in psychiatric and non-psychiatric disorders and to discuss the potential role of NLR in psychiatric research. CONCLUSIONS: NLR is inexpensive and readily available using division of two measures obtained on routine blood testing. NLR is elevated in a number of psychiatric disorders. It can predict morbidity and mortality in a wide range of non-psychiatric conditions, but this has not been confirmed in psychiatric conditions. It can be calculated in large, pre-existing datasets to investigate clinical correlates of inflammatory processes. NLR may have a future role in identifying patients with an inflammatory phenotype who could benefit from adjunctive anti-inflammatory medications.|
|Keywords:||neutrophil–lymphocyte ratio; inflammatory marker; morbidity; psychiatric disorders; prognosis|
|Rights:||© The Royal Australian and New Zealand College of Psychiatrists 2020|
|Appears in Collections:||Psychiatry publications|
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