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Type: Journal article
Title: Genetic analysis of deciduous tooth size in Australian twins
Author: Hughes, T.
Dempsey, P.
Richards, L.
Townsend, G.
Citation: Archives of Oral Biology, 2000; 45(11):997-1004
Publisher: Pergamon-Elsevier Science Ltd
Issue Date: 2000
ISSN: 0003-9969
Abstract: Investigations of permanent dental crown size in twins and family groups indicate a high degree of transmissible control, but little is known about the relative contributions of genetic and environmental factors to variation in size of the deciduous (primary) teeth. Here, maximum mesiodistal and buccolingual crown dimensions of maxillary and mandibular primary teeth were measured from dental models of 602 individuals, including 99 monozygous (MZ) twin pairs, 81 dizygous (DZ) same-sex pairs, 41 DZ opposite-sex pairs, and 160 singletons. Data were subjected to univariate genetic analysis with the structural-equation-modelling package, Mx using the normal assumptions of the twin model. A model incorporating additive genetic (A) and unique environmental (E) variation was found to be the most parsimonious for all tooth-size variables. Estimates of heritability for deciduous crown size ranged from 0.62 to 0.91. This study shows that variation in deciduous crown size has a strong genetic component, similar to that observed in the permanent dentition. Further studies are required to determine whether the underlying genetic mechanisms are the same for both deciduous and permanent teeth.
Keywords: Mandible
Tooth, Deciduous
Tooth Crown
Analysis of Variance
Chi-Square Distribution
Sex Factors
Twins, Dizygotic
Twins, Monozygotic
Models, Genetic
Child, Preschool
Models, Dental
DOI: 10.1016/S0003-9969(00)00066-2
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Dentistry publications

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