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Type: Journal article
Title: Cutaneous squamous carcinoma in situ (Bowen's disease): Treatment with Mohs micrographic surgery
Author: Leibovitch, I.
Huilgol, S.
Selva-Nayagam, D.
Richards, S.
Paver, R.
Citation: Journal of the American Academy of Dermatology, 2005; 52(6):997-1002
Publisher: Mosby Inc
Issue Date: 2005
ISSN: 0190-9622
Abstract: <h4>Background</h4>Bowen's disease (BD), also known as squamous intraepidermal carcinoma, is a malignant skin tumor with a potential to progress to invasive carcinoma.<h4>Objective</h4>We sought to report a large series of patients with BD treated with Mohs micrographic surgery (MMS).<h4>Methods</h4>This prospective, multicenter, case series included all patients in Australia treated with MMS for BD, who were monitored by the Skin and Cancer Foundation between 1993 and 2002.<h4>Results</h4>There were 270 cases; the majority (93.4%) were located in the head and neck area. In 50.7% of cases it was a recurrent tumor. In 20% the tumor was initially misdiagnosed as basal cell carcinoma or squamous cell carcinoma. No cases with perineural invasion were diagnosed. There were 6 cases of recurrence (6.3%) of 95 patients who completed a 5-year follow-up period after MMS.<h4>Conclusion</h4>The low 5-year recurrence rate of BD with MMS emphasizes the importance of margin-controlled excision, especially in the head and neck area where tissue preservation is essential.
Keywords: Humans
Bowen's Disease
Skin Neoplasms
Mohs Surgery
Prospective Studies
Aged, 80 and over
Middle Aged
DOI: 10.1016/j.jaad.2004.12.033
Appears in Collections:Aurora harvest 6
Surgery publications

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