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https://hdl.handle.net/2440/16681
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Type: | Journal article |
Title: | Cutaneous squamous carcinoma in situ (Bowen's disease): Treatment with Mohs micrographic surgery |
Author: | Leibovitch, I. Huilgol, S. Selva-Nayagam, D. Richards, S. Paver, R. |
Citation: | Journal of the American Academy of Dermatology, 2005; 52(6):997-1002 |
Publisher: | Mosby Inc |
Issue Date: | 2005 |
ISSN: | 0190-9622 1097-6787 |
Abstract: | <h4>Background</h4>Bowen's disease (BD), also known as squamous intraepidermal carcinoma, is a malignant skin tumor with a potential to progress to invasive carcinoma.<h4>Objective</h4>We sought to report a large series of patients with BD treated with Mohs micrographic surgery (MMS).<h4>Methods</h4>This prospective, multicenter, case series included all patients in Australia treated with MMS for BD, who were monitored by the Skin and Cancer Foundation between 1993 and 2002.<h4>Results</h4>There were 270 cases; the majority (93.4%) were located in the head and neck area. In 50.7% of cases it was a recurrent tumor. In 20% the tumor was initially misdiagnosed as basal cell carcinoma or squamous cell carcinoma. No cases with perineural invasion were diagnosed. There were 6 cases of recurrence (6.3%) of 95 patients who completed a 5-year follow-up period after MMS.<h4>Conclusion</h4>The low 5-year recurrence rate of BD with MMS emphasizes the importance of margin-controlled excision, especially in the head and neck area where tissue preservation is essential. |
Keywords: | Humans Bowen's Disease Skin Neoplasms Mohs Surgery Prospective Studies Adult Aged Aged, 80 and over Middle Aged Female Male |
DOI: | 10.1016/j.jaad.2004.12.033 |
Published version: | http://dx.doi.org/10.1016/j.jaad.2004.12.033 |
Appears in Collections: | Aurora harvest 6 Surgery publications |
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