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https://hdl.handle.net/2440/17143
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dc.contributor.author | Need, A. | - |
dc.contributor.author | O'Loughlin, P. | - |
dc.contributor.author | Horowitz, M. | - |
dc.contributor.author | Nordin, B. | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | Clinical Endocrinology, 2005; 62(6):738-741 | - |
dc.identifier.issn | 0300-0664 | - |
dc.identifier.issn | 1365-2265 | - |
dc.identifier.uri | http://hdl.handle.net/2440/17143 | - |
dc.description | The definitive version is available at www.blackwell-synergy.com | - |
dc.description.abstract | Objective: Because it has been reported that vitamin D, given to mother or infant, can prevent type I diabetes in children, that diabetes is more common in adults with low serum vitamin D and that insulin secretion and action are related to vitamin D levels in healthy young adults we examined the relationship between serum vitamin D metabolites and fasting serum glucose in patients attending our outpatient clinics. Design: Retrospective examination of convenience sample of postmenopausal women attending our osteoporosis clinics. Patients: A total of 753 postmenopausal women attending a university hospital outpatient clinic and not on any treatment known to affect glucose metabolism. Measurements: Body weight and height, serum 25- hydroxyvitamin D [25(OH)D], serum 1,25-dihydroxyvitamin D [1,25(OH) 2 D], serum PTH and fasting serum glucose. Results: On simple correlation fasting serum glucose was a positive function of age (P < 0·05), weight (P < 0·001) and body mass index (BMI) (P < 0·001) and a negative function of serum 25(OH)D (P < 0·001), but it was not significantly related to either serum 1,25(OH) 2 D, PTH or creatinine. When fasting serum glucose was regressed simultaneously on age, BMI and 25(OH)D, glucose was still an inverse function of 25(OH)D (P = 0·006). Conclusions: Fasting serum glucose increased as 25(OH)D levels fell throughout the range of serum 25(OH)D measured but the greatest increase was observed in those with 25(OH)D below 40 nmol/ l. | - |
dc.description.statementofresponsibility | Allan G. Need, Peter D. O’Loughlin, Michael Horowitz and B. E. Christopher Nordin | - |
dc.language.iso | en | - |
dc.publisher | Blackwell Science Ltd | - |
dc.source.uri | http://dx.doi.org/10.1111/j.1365-2265.2005.02288.x | - |
dc.subject | Humans | - |
dc.subject | Diabetes Mellitus, Type 2 | - |
dc.subject | Creatinine | - |
dc.subject | Calcifediol | - |
dc.subject | Parathyroid Hormone | - |
dc.subject | Blood Glucose | - |
dc.subject | Vitamin D | - |
dc.subject | Body Mass Index | - |
dc.subject | Fasting | - |
dc.subject | Risk Factors | - |
dc.subject | Regression Analysis | - |
dc.subject | Postmenopause | - |
dc.subject | Adult | - |
dc.subject | Aged | - |
dc.subject | Aged, 80 and over | - |
dc.subject | Middle Aged | - |
dc.subject | Female | - |
dc.subject | White People | - |
dc.title | Relationship between fasting serum glucose, age, body mass index and serum 25 hydroxyvitamin D in postmenopausal women | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1111/j.1365-2265.2005.02288.x | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Horowitz, M. [0000-0002-0942-0306] | - |
Appears in Collections: | Aurora harvest 6 Pathology publications |
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