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Type: Journal article
Title: The enigma of hypertensive ESRD: Observations on incidence and trends in 18 European, Canadian, and Asian-Pacific populations, 1998 to 2002
Author: Stewart, J.
McCredie, M.
Williams, S.
Jager, K.
Trpeski, L.
McDonald, S.
Citation: American Journal of Kidney Diseases, 2006; 48(2):183-191
Publisher: W B Saunders Co
Issue Date: 2006
ISSN: 0272-6386
Abstract: <h4>Background</h4>Despite improved treatment of hypertension and decreasing rates of stroke and coronary heart disease, the reported incidence of hypertensive end-stage renal disease (ESRD) increased during the 1990s. However, bias, particularly from variations in acceptance into ESRD treatment (ascertainment) and diagnosis (classification), has been a major source of error when comparing ESRD incidences or estimating trends.<h4>Methods</h4>Age-standardized rates were calculated in persons aged 30 to 44, 45 to 64, and 65 to 74 years for 15 countries or regions (separately for the Europid and non-Europid populations of Canada, Australia, and New Zealand), and temporal trends were estimated by means of Poisson regression. For 10 countries or regions, population-based estimates of mean systolic blood pressures and prevalences of hypertension were extracted from published sources.<h4>Results</h4>Hypertensive ESRD, comprising ESRD attributed to essential hypertension or renal artery occlusion, was least common in Finland, non-Aboriginal Australians, and non-Polynesian New Zealanders; intermediate in most European and Canadian populations; and most common in Aboriginal Australians and New Zealand Maori and Pacific Island people. Rates correlated with the incidence of all other nondiabetic ESRD, but not with diabetic ESRD or community rates of hypertension. Between 1998 and 2002, hypertensive ESRD did not increase in Northwestern Europe or non-Aboriginal Canadians, although it did so in Australia.<h4>Conclusion</h4>Despite the likelihood of classification bias, the probability remains of significant variation in incidence of hypertensive ESRD within the group of Europid populations. These between-population differences are not explained by community rates of hypertension or ascertainment bias.
Keywords: Canadian Organ Replacement Register
Australia and New Zealand Dialysis and Transplant Registry
European Renal Association-European Dialysis and Transplant Association Registry
Finnish Registry for Kidney Diseases
Swedish Registry for Active Treatment of Uremia
Norwegian Renal Registry
Danish National Registry on Regular Dialysis and Transplantation
Dutch-speaking Belgian Society of Nephrology
Austrian Dialysis and Transplant Registry
Basque Renal Patients' Registry
Catalan Renal Registry
Valencian Renal Registry
Hellenic Renal Registry
Malaysian National Renal Registry
Kidney Failure, Chronic
Diabetes Complications
Epidemiologic Studies
Middle Aged
New Zealand
Native Hawaiian or Other Pacific Islander
DOI: 10.1053/j.ajkd.2006.04.067
Appears in Collections:Aurora harvest 6
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