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|Title:||Avian riboflavin deficiency: An acquired tomaculous neuropathy|
|Citation:||Veterinary Pathology, 2006; 43(5):780-781|
|Publisher:||Amer Coll Vet Pathologist|
|Abstract:||The finding of tomacula, focal areas of sausage-shaped hypermyelination in peripheral nerves, is reported for the first time in avian riboflavin deficiency. Day-old, meat-type chickens were fed a riboflavin-deficient diet (1.8 mg/kg) and were killed on postnatal days 6, 11, 16, and 21, while control chickens were fed a conventional diet containing 5.0 mg/kg riboflavin. Tomacula were found in sciatic and brachial nerves from day 11 onward, became more frequent and prominent with increasing time, and preceded the onset of segmental demyelination.|
|Keywords:||avian; peripheral nerve; riboflavin deficiency; tomacula|
|Appears in Collections:||Pathology publications|
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