Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/23231
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Type: Journal article
Title: RANK expression as a cell surface marker of human osteoclast precursors in peripheral blood, bone marrow, and giant cell tumors of bone
Author: Atkins, G.
Kostakis, P.
Vincent, C.
Farrugia, A.
Houchins, J.
Findlay, D.
Evdokiou, A.
Zannettino, A.
Citation: Journal of Bone and Mineral Research, 2006; 21(9):1339-1349
Publisher: Amer Soc Bone & Mineral Res
Issue Date: 2006
ISSN: 0884-0431
1523-4681
Statement of
Responsibility: 
Gerald J Atkins, Panagiota Kostakis, Cristina Vincent, Amanda N Farrugia, Jeffrey P Houchins, David M Findlay, Andreas Evdokiou, and Andrew CW Zannettino
Abstract: RANK expression in vivo on hematopoietic subsets including pre-osteoclasts, identified by monoclonal antibodies, has not been described. We describe the lineages that express RANK in bone marrow, peripheral blood, and GCTs. We show that CD14+RANKhigh cells constitute a circulating pre-osteoclast pool.
Keywords: RANK; hematopoietic cells; giant cell tumor; monoclonal antibodies
Description: © 2006 American Society for Bone and Mineral Research
RMID: 0020061352
DOI: 10.1359/jbmr.060604
Published version: http://www.jbmronline.org/doi/abs/10.1359/jbmr.060604
Appears in Collections:Orthopaedics and Trauma publications

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