Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/42903
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Type: Journal article
Title: Internal carotid artery hemorrhage after irradiation and osteoradionecrosis of the skull base
Author: Lam, H.
Abdullah, V.
Wormald, P.
van Hasselt, C.
Citation: Otolaryngology-Head and Neck Surgery, 2001; 125(5):522-527
Publisher: Mosby Inc
Issue Date: 2001
ISSN: 0194-5998
1097-6817
Statement of
Responsibility: 
Henry Chuen Kwong Lam, Victor James Abdullah, Peter John Wormald and Charles Andrew Van Hasselt
Abstract: <h4>Objective</h4>To evaluate the clinical presentation and management of internal carotid artery rupture after irradiation and osteoradionecrosis of the skull base.<h4>Study design and setting</h4>A retrospective review of the patients in an otorhinolaryngology-head and neck secondary and tertiary referral center.<h4>Methodology</h4>From January 1993 to December 1996, patients with hemorrhage from internal carotid artery as a complication of irradiation and osteoradionecrosis of skull base were reviewed and analyzed.<h4>Results</h4>Four patients with internal carotid arterial rupture were included in this study. Angiography was performed in all cases. Embolization of the aneurysm was performed on 2 patients and the remaining 2 patients underwent occlusion of their internal carotid arteries. Three of the 4 patients did not survive. The fourth is currently alive and well 18 months after embolization of 1 internal carotid artery.<h4>Conclusion</h4>Skull base osteoradionecrosis with bleeding from internal carotid artery is a potentially fatal complication of irradiation. Angiography was the mainstay of diagnosis with embolization of the aneurysm and embolization or ligation of the internal carotid artery being the management options. Internal carotid artery occlusion is the definitive treatment provided cross circulation is adequate.<h4>Significance</h4>The advantages and disadvantages of the treatment options are discussed and a management protocol is proposed.
Keywords: Skull Base; Carotid Artery, Internal; Humans; Nasopharyngeal Neoplasms; Carotid Artery Diseases; Aneurysm, False; Osteoradionecrosis; Rupture, Spontaneous; Hemorrhage; Radiotherapy; Aged; Middle Aged; Male
Description: Copyright © 2001 American Academy of Otolaryngology-Head and Neck Surgery Foundation, Inc Published by Mosby, Inc.
RMID: 0020076432
DOI: 10.1067/mhn.2001.118248
Description (link): http://journals.elsevierhealth.com/periodicals/ymhn/home
Appears in Collections:Surgery publications

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