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Type: Journal article
Title: Effect of remineralization/demineralization cycles on mineral profiles of Fuji IX Fast in vitro using electron probe microanalysis
Author: AbGhani, Z.
Ngo, H.
McIntyre, J.
Citation: Australian Dental Journal, 2007; 52(4):276-281
Publisher: Australian Dental Assn Inc
Issue Date: 2007
ISSN: 0045-0421
Abstract: Background: There have been concerns about the dissolution of conventional glass ionomer cement (GIC) and its possible degradation when exposed to an acidic environment over time. The objective of this study was to investigate the effects of exposure of Fuji IX Fast to the simulated acidic aspects of the oral environment in terms of any changes in the elemental composition of strontium (Sr), phosphorus (P), calcium (Ca) and fluorine (F) which resulted at the surface of this material. Methods: Sixty-five cylindrical blocks of Fuji IX Fast were prepared using split moulds. The demineralizing solution was an acetate buffered demineralizing solution at pH 4.3. The remineralizing solution was a buffered solution containing 1.5 mM Ca, 0.9 mM P and 10 ppm F at pH 7. The blocks of Fuji IX Fast were subjected either to two-day alternating cycles of remineralization and demineralization for up to 24 days (test); 6 two-day cycles of demineralizing or remineralizing solution separately, or deionized distilled water alone (controls) or were left untreated (base line control). Mineral profiles of Ca, P, Sr and F within 100 μm of the material surface were assessed following 8, 16 and 24 days of treatment (test); 4, 8 or 12 days (controls) or for baseline control samples, using electron probe microanalysis (EPMA). Results: There were significant changes in mineral profile in the test specimens in terms of Sr and Ca concentrations. A molecule for molecule exchange of these elements resulted between GIC and eluant solutions. Fluoride loss from the GIC occurred to the level comparable with uptake levels recorded in eluant solutions from previous studies. The ionic exchanges appeared to be the result of dissolution followed by an equilibrium-driven diffusion. These exchanges were superficial though substantial. Conclusions: Simulated exposure of Fuji IX to the oral environment resulted in an exchange of Ca from the bathing solutions into Fuji IX to replace any Sr which was lost to the GIC. Fluorine loss from the GIC followed previously described patterns. The possible clinical significance of this exchange was discussed.
Description: The definitive version can be found at
RMID: 0020074728
DOI: 10.1111/j.1834-7819.2007.tb00502.x
Appears in Collections:Dentistry publications

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