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https://hdl.handle.net/2440/43416
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Type: | Journal article |
Title: | Can EGCG reduce abdominal fat in obese subjects? |
Author: | Hill, A. Coates, A. Buckley, J. Ross, R. Thielecke, F. Howe, P. |
Citation: | Journal of the American College of Nutrition, 2007; 26(4):396S-402S |
Publisher: | Amer Coll Nutrition |
Issue Date: | 2007 |
ISSN: | 0731-5724 1541-1087 |
Statement of Responsibility: | Alison M. Hill, Alison M. Coates, Jonathan D. Buckley, Robert Ross, Frank Thielecke and Peter R.C. Howe |
Abstract: | <h4>Objective</h4>To evaluate metabolic effects of epigallocatechin gallate (EGCG) supplementation when combined with a program of regular aerobic exercise in overweight/obese post-menopausal women.<h4>Methods</h4>Thirty-eight overweight or obese postmenopausal women exercised at moderate intensity, viz. walking three times per week for 45 min at 75% of age-predicted maximum heart rate (HR), and took a 150 mg capsule of EGCG (Teavigo) or placebo (lactose) twice daily for 12 weeks. Blood parameters (lipids, glucose and insulin), blood pressure, heart rate, arterial function and anthropometry were assessed at 0, 6 and 12 wk. At wk 0 and 12, body composition was assessed by dual energy X-ray absorptiometry (DXA) and abdominal fat was assessed by DXA and computed tomography (CT).<h4>Results</h4>Waist circumference (p < 0.01), total body fat (p < 0.02), abdominal fat (by DXA) (p < 0.01) and intra abdominal adipose tissue (by CT) (p < 0.01) were reduced in both treatment groups, with no difference between placebo and Teavigo. Teavigo significantly decreased resting HR (p < 0.01) and reduced plasma glucose in subjects with impaired glucose tolerance (p < 0.05).<h4>Conclusions</h4>Moderate consumption of EGCG can improve the health status of overweight individuals undergoing regular exercise by reducing HR and plasma glucose concentrations. Loss of body fat, however, may require a higher intake of EGCG, other catechins or addition of metabolic stimulants. |
Keywords: | Humans Obesity Weight Loss Catechin Blood Glucose Body Mass Index Waist-Hip Ratio Treatment Outcome Walking Health Status Body Composition Postmenopause Heart Rate Dietary Supplements Aged Middle Aged Female Abdominal Fat Overweight |
Description: | Copyright © 2007 by the American College of Nutrition. |
DOI: | 10.1080/07315724.2007.10719628 |
Published version: | http://www.jacn.org/cgi/content/abstract/26/4/396S |
Appears in Collections: | Aurora harvest Molecular and Biomedical Science publications |
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