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Type: Journal article
Title: Carbapenem Resistance among Pseudomonas aeruginosa Strains from India: Evidence for Nationwide Endemicity of Multiple Metallo-beta-Lactamase Clones (VIM-2,-5,-6, and-11 and the Newly Characterized VIM-18)
Author: Castanheira, M.
Bell, J.
Turnidge, J.
Mathai, D.
Jones, R.
Citation: Antimicrobial Agents and Chemotherapy, 2009; 53(3):1225-1227
Publisher: Amer Soc Microbiology
Issue Date: 2009
ISSN: 0066-4804
Statement of
Mariana Castanheira, Jan M. Bell, John D. Turnidge, Dillip Mathai and Ronald N. Jones
Abstract: Among 57 metallo-beta-lactamase (MbetaL)-producing Pseudomonas spp. detected in India during 2006, five bla(VIM) genes were found, including a newly characterized bla(VIM) gene. Pseudomonas aeruginosa strains were clustered in 33 ribotypes with clones found in multiple hospitals. Several types of bla(VIM-2)-carrying integrons were detected. The newly characterized variant VIM-18 showed a 4-amino-acid deletion compared to other VIM variants. In this study, we show that VIM-producing Pseudomonas spp. were highly prevalent in India with a great diversity of bla(VIM) types and MbetaL-carrying integrons.
Keywords: Humans
Pseudomonas aeruginosa
Bacterial Proteins
Anti-Bacterial Agents
Microbial Sensitivity Tests
Drug Resistance, Bacterial
Base Sequence
Molecular Sequence Data
DOI: 10.1128/AAC.01011-08
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Appears in Collections:Aurora harvest
Molecular and Biomedical Science publications

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