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https://hdl.handle.net/2440/55326
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Type: | Journal article |
Title: | Is this D Vitamin to worry about? Vitamin D insufficiency in an inpatient sample |
Author: | Berk, M. Jacka, F. Williams, L. Ng, F. Dodd, S. Pasco, J. |
Citation: | Australian and New Zealand Journal of Psychiatry, 2008; 42(10):874-878 |
Publisher: | Blackwell Publishing Asia |
Issue Date: | 2008 |
ISSN: | 0004-8674 1440-1614 |
Statement of Responsibility: | Michael Berk, Felice N. Jacka, Lana J. Williams, Felicity Ng, Seetal Dodd and Julie A. Pasco |
Abstract: | Objective: The aim of the present study was to investigate the relationship between reduced serum vitamin D levels and psychiatric illness. Method: This study was an audit of serum 25-hydroxyvitamin D (25-OHD) levels measured routinely in a sample of 53 inpatients in a private psychiatric clinic. These levels were compared with those of controls without psychiatric illness. Results: The median levels of serum 25-OHD were 43.0 nmol L−1 (range 20–102 nmol L−1) in the patient population, 46.0 nmol L−1 (range 20–102 nmol L−1) in female patients (n =33) and 41.5 nmol L−1 (range 22–97 nmol L−1) in male patients (n =20). The proportion of vitamin D insufficiency (serum 25-OHD ≤50 nmol L−1) in this patient population was 58%. Furthermore, 11% had moderate deficiency (serum 25-OHD ≤25 nmol L−1). There was a 29% difference between mean levels in the patient population and control sample (geometric mean age- and season-adjusted levels: 46.4 nmol L−1 (95% confidence interval (CI) =38.6–54.9 nmol L−1) vs 65.3 nmol L−1 (95%CI =63.2–67.4 nmol L−1), p <0.001). Conclusion: Low levels of serum 25-OHD were found in this patient population. These data add to the literature suggesting an association between vitamin D insufficiency and psychiatric illness, and suggest that routine monitoring of vitamin D levels may be of benefit given the high yield of clinically relevant findings. |
Keywords: | Humans Bone Diseases, Metabolic Vitamin D Deficiency Vitamin D Hospitalization Depressive Disorder, Major Seasons Bone Density Adult Aged Aged, 80 and over Middle Aged Hospitals, Private Female Male Young Adult |
DOI: | 10.1080/00048670802345516 |
Published version: | http://dx.doi.org/10.1080/00048670802345516 |
Appears in Collections: | Aurora harvest 5 Psychiatry publications |
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