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Type: Journal article
Title: Pathogenesis of orbital cholesterol granuloma
Author: Selva-Nayagam, D.
Phipps, S.
O'Connell, J.
White, V.
Rootman, J.
Citation: Clinical and Experimental Ophthalmology, 2003; 31(1):78-82
Publisher: Blackwell Publishing Asia
Issue Date: 2003
ISSN: 1442-6404
Statement of
Dinesh Selva, Simon E. Phipps, John X. O’Connell, Valerie A. White and Jack Rootman
Abstract: Two cases are presented of orbital cholesterol granuloma associated with gradual proptosis arising in men aged 35 and 41 years. Computed tomography demonstrated osteo-lytic masses in the frontal bone at the lacrimal fossa. Curettage revealed a characteristic histology of foreign body reactions surrounding cholesterol clefts. In both cases abnormal bone, more consistent with fibrous dysplasia than reactive change, was found at the periphery. The finding of abnormal bone associated with orbital cholesterol granulomas suggests that a pre-existing bone anomaly may be present in a subset of these cases.
Keywords: cholesterol granuloma
fibrous dysplasia
frontal bone
osteolytic lesion.
Description: Journal compilation © 2008 Royal Australian and New Zealand College of Ophthalmologists
DOI: 10.1046/j.1442-9071.2003.00605.x
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