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https://hdl.handle.net/2440/58230
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dc.contributor.author | Sjoberg, N. | - |
dc.contributor.author | Milte, C. | - |
dc.contributor.author | Buckley, J. | - |
dc.contributor.author | Howe, P. | - |
dc.contributor.author | Coates, A. | - |
dc.contributor.author | Saint, D. | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | The British Journal of Nutrition: an international journal of nutritional science, 2010; 103(2):243-248 | - |
dc.identifier.issn | 0007-1145 | - |
dc.identifier.issn | 1475-2662 | - |
dc.identifier.uri | http://hdl.handle.net/2440/58230 | - |
dc.description.abstract | Heart rate (HR) variability and large arterial compliance can be improved using fish oils. DHA, a component of fish oil, has cardiovascular health benefits, but its effect on HR variability (HRV) and arterial compliance is yet to be quantified. Sixty-seven overweight or obese adults (thirty-six males and thirty-one females; 53 (SEM 2) year; BMI 31•7 (SEM 1•1) kg/m2) were randomly allocated to consume either 6 g/d sunola oil (control; n 17), fish oil (260 mg DHA þ 60 mg EPA per g) at doses of 2 g/d (n 16), 4 g/d (n 17) or 6 g/d (n 17). Blood pressure, HR and compliance of large and small arteries were measured while supine at baseline and after 12 weeks in all participants, and HRV was assessed in a subgroup of forty-six participants. There was no effect of fish oil on blood pressure, small artery compliance or HR. However, the low frequency:high frequency ratio of HRV decreased with increasing doses of fish oil (r 20•34, P¼0•02), while large artery compliance increased (r 0•34, P¼0•006). Moreover, the changes in these biomarkers were significantly correlated (r 20•31, P¼0•04) and may reflect fish oil-induced improvements in arterial function and cardiac autonomic regulation. | - |
dc.description.statementofresponsibility | Nicholas J. Sjoberg, Catherine M. Milte, Jonathan D. Buckley, Peter R. C. Howe, Alison M. Coates and David A. Saint | - |
dc.language.iso | en | - |
dc.publisher | C A B I Publishing | - |
dc.rights | Copyright The Authors 2009 | - |
dc.source.uri | http://dx.doi.org/10.1017/s000711450999153x | - |
dc.subject | n-3 PUFA | - |
dc.subject | DHA | - |
dc.subject | Cardiovascular health | - |
dc.subject | Cardiac autonomic balance | - |
dc.title | Dose-dependent increases in heart rate variability and arterial compliance in overweight and obese adults with DHA-rich fish oil supplementation | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1017/S000711450999153X | - |
dc.relation.grant | http://purl.org/au-research/grants/arc/LP0561211 | - |
dc.relation.grant | http://purl.org/au-research/grants/arc/LP0561211 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Howe, P. [0000-0001-6546-7742] | - |
Appears in Collections: | Aurora harvest Molecular and Biomedical Science publications |
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