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PreviewIssue DateTitleAuthor(s)
2019OBI-3424, a novel AKR1c3-activated prodrug, exhibits potent efficacy against preclinical models of T-ALLEvans, K.; Duan, J.X.; Pritchard, T.; Jones, C.D.; McDermott, L.; Gu, Z.; Toscan, C.E.; El-Zein, N.; Mayoh, C.; Erickson, S.W.; Guo, Y.; Meng, F.; Jung, D.; Rathi, K.S.; Roberts, K.G.; Mullighan, C.G.; Shia, C.S.; Pearce, T.; Teicher, B.A.; Smith, M.A.; et al.
2019Disruptive variants of CSDE1 associate with autism and interfere with neuronal development and synaptic transmissionGuo, H.; Li, Y.; Shen, L.; Wang, T.; Jia, X.; Liu, L.; Xu, T.; Ou, M.; Hoekzema, K.; Wu, H.; Gillentine, M.A.; Liu, C.; Ni, H.; Peng, P.; Zhao, R.; Zhang, Y.; Phornphutkul, C.; Stegmann, A.P.A.; Prada, C.E.; Hopkin, R.J.; et al.
2019Dietary zinc and the control of Streptococcus pneumoniae infectionEijkelkamp, B.A.; Morey, J.R.; Neville, S.L.; Tan, A.; Pederick, V.G.; Cole, N.; Singh, P.P.; Ong, C.-L.Y.; Gonzalez de Vega, R.; Clases, D.; Cunningham, B.A.; Hughes, C.E.; Comerford, I.; Brazel, E.B.; Whittall, J.J.; Plumptre, C.D.; McColl, S.R.; Paton, J.C.; McEwan, A.G.; Doble, P.A.; et al.; Orihuela, C.J.
2019A heritable subset of the core rumen microbiome dictates dairy cow productivity and emissionsJohn Wallace, R.; Sasson, G.; Garnsworthy, P.C.; Tapio, I.; Gregson, E.; Bani, P.; Huhtanen, P.; Bayat, A.R.; Strozzi, F.; Biscarini, F.; Snelling, T.J.; Saunders, N.; Potterton, S.L.; Craigon, J.; Minuti, A.; Trevisi, E.; Callegari, M.L.; Cappelli, F.P.; Cabezas-Garcia, E.H.; Vilkki, J.; et al.
2019Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemiaMoujalled, D.M.; Pomilio, G.; Ghiurau, C.; Ivey, A.; Salmon, J.; Rijal, S.; Macraild, S.; Zhang, L.; Teh, T.C.; Tiong, I.S.; Lan, P.; Chanrion, M.; Claperon, A.; Rocchetti, F.; Zichi, A.; Kraus-Berthier, L.; Wang, Y.; Halilovic, E.; Morris, E.; Colland, F.; et al.
2019DNA hypermethylation encroachment at CpG island borders in cancer is predisposed by H3K4 monomethylation patternsSkvortsova, K.; Masle-Farquhar, E.; Luu, P.L.; Song, J.Z.; Qu, W.; Zotenko, E.; Gould, C.M.; Du, Q.; Peters, T.J.; Colino-Sanguino, Y.; Pidsley, R.; Nair, S.S.; Khoury, A.; Smith, G.C.; Miosge, L.A.; Reed, J.H.; Kench, J.G.; Rubin, M.A.; Horvath, L.; Bogdanovic, O.; et al.
2019Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemiaBell, C.C.; Fennell, K.A.; Chan, Y.C.; Rambow, F.; Yeung, M.M.; Vassiliadis, D.; Lara, L.; Yeh, P.; Martelotto, L.G.; Rogiers, A.; Kremer, B.E.; Barbash, O.; Mohammad, H.P.; Johanson, T.M.; Burr, M.L.; Dhar, A.; Karpinich, N.; Tian, L.; Tyler, D.S.; MacPherson, L.; et al.