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PreviewIssue DateTitleAuthor(s)
2013Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-c and extracellular cyclic guanosine 3′,5′-monophosphateCastro, J.; Harrington, A.; Hughes, P.; Martin, C.; Ge, P.; Shea, C.; Jin, H.; Jacobson, S.; Hannig, G.; Mann, E.; Cohen, M.; MacDougall, J.; Lavins, B.; Kurtz, C.; Silos-Santiago, I.; Johnston, J.; Blackshaw, L.; Brierley, S.
2017Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signallingHughes, J.; Dawson, R.; Tea, M.; McAninch, D.; Piltz, S.; Jackson, D.; Stewart, L.; Ricos, M.; Dibbens, L.; Harvey, N.; Thomas, P.
2017NAD deficiency, congenital malformations, and niacin supplementationShi, H.; Enriquez, A.; Rapadas, M.; Martin, E.; Wang, R.; Moreau, J.; Lim, C.; Szot, J.; Ip, E.; Hughes, J.; Sugimoto, K.; Humphreys, D.; McInerney-Leo, A.; Leo, P.; Maghzal, G.; Halliday, J.; Smith, J.; Colley, A.; Mark, P.; Collins, F.; et al.
2019Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in femalesJackson, M.R.; Loring, K.E.; Homan, C.C.; Thai, H.N.; Määttänen, L.; Arvio, M.; Jarvela, I.; Shaw, M.; Gardner, A.; Gecz, J.; Shoubridge, C.
2012Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense against bacterial urinary tract InfectionDuell, B.; Carey, A.; Tan, C.; Cui, X.; Webb, R.; Totsika, M.; Schembri, M.; Derrington, P.; Irving-Rodgers, H.; Brooks, A.; Cripps, A.; Crowley, M.; Ulett, G.
2016Topical application of fingolimod perturbs cutaneous inflammationSun, W.Y.; Dimasi, D.P.; Pitman, M.R.; Zhuang, Y.; Heddle, R.; Pitson, S.M.; Grimbaldeston, M.A.; Bonder, C.S.
2014Zinc and zinc transporters in macrophages and their roles in efferocytosis in COPDHamon, R.; Homan, C.; Tran, H.; Mukaro, V.; Lester, S.; Roscioli, E.; Bosco, M.; Murgia, C.; Ackland, M.; Jersmann, H.; Lang, C.; Zalewski, P.; Hodge, S.; Adlard, P.A.
2013Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertensionRonzaud, C.; Loffing-Cueni, D.; Hausel, P.; Debonneville, A.; Malsure, S.; Fowler-Jaeger, N.; Boase, N.; Perrier, R.; Maillard, M.; Yang, B.; Stokes, J.; Koesters, R.; Kumar, S.; Hummler, E.; Loffing, J.; Staub, O.
2012Glucokinase links Kruppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver diseaseBechmann, L.; Gastaldelli, A.; Vetter, D.; Patman, G.; Pascoe, L.; Hannivoort, R.; Lee, U.; Fiel, I.; Munoz, U.; Ciociaro, D.; Lee, Y.; Buzzigoli, E.; Miele, L.; Hui, K.; Bugianesi, E.; Burt, A.; Day, C.; Mari, A.; Agius, L.; Walker, M.; et al.
2012Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instabilityDorstyn, L.; Puccini, J.; Wilson, C.; Shalini, S.; Nicola, M.; Moore, S.; Kumar, S.