Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/60748
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Type: | Journal article |
Title: | Prevalence and determinants of age-related macular degeneration in central Sri Lanka: the Kandy Eye Study |
Author: | Goold, L. Edussuriya, K. Sennanayake, S. Senaratne, T. Selva-Nayagam, D. Sullivan, T. Casson, R. |
Citation: | British Journal of Ophthalmology, 2010; 94(2):150-153 |
Publisher: | British Med Journal Publ Group |
Issue Date: | 2010 |
ISSN: | 0007-1161 1468-2079 |
Statement of Responsibility: | L A Goold, K Edussuriya, S Sennanayake, T Senaratne, D Selva, T R Sullivan, R J Casson |
Abstract: | Aims To determine the prevalence, associations and risk factors for age-related macular degeneration (ARMD) in central Sri Lanka. Methods The study was a population-based, cross-sectional survey of residents aged ≥40 years in rural Sri Lanka. ARMD was assessed on dilated fundoscopy using the International Age-Related Maculopathy Epidemiology Study Group classification system. Results Of the 1721 subjects identified, 1375 participated (79.9%). Of the participants, 1013 were aged ≥50 years (73.6%). The prevalence of any ARMD (adjusted for study design) was 4.72 (95% CI 2.22 to 7.20)% with 3.82 (95% CI 1.60 to 6.04)% early ARMD and 1.70 (95% CI 0.14 to 3.27)% late ARMD. Age (p<0.001) and Sinhalese ethnicity (p = 0.016) were significantly associated with ARMD. Men had a tendency toward a higher prevalence of ARMD than women, although this was not statistically significant (p = 0.081). Ocular risk factors such as cortical cataract (p = 0.024) and pseudophakia (p = 0.003) were associated with ARMD on the univariate but not multivariate analyses. Illiteracy and the identification of social supports were significantly associated with ARMD on univariate analyses. However, only social support was statistically significant after multivariate analysis (p = 0.024). Conclusions Although the prevalence of ARMD is slightly lower in Sri Lanka than surrounding regions, it contributes to a higher proportion of visual impairment, including blindness. Risk factors include age and Sinhalese ethnicity. |
Keywords: | Humans Vision Disorders Blindness Macular Degeneration Epidemiologic Methods Age Factors Sex Factors Age Distribution Aged Middle Aged Rural Health Sri Lanka Female Male |
Rights: | Copyright © 2010 The Authors |
DOI: | 10.1136/bjo.2009.163808 |
Published version: | http://dx.doi.org/10.1136/bjo.2009.163808 |
Appears in Collections: | Aurora harvest 5 Public Health publications |
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